Effect of Carrier Lipophilicity and Preparation Method on the Properties of Andrographolide-Solid Dispersion

• Ngā kaituhi matua: Guowei Zhao (Author), Qingyun Zeng (Author), Shoude Zhang (Author), Youquan Zhong (Author), Changhao Wang (Author), Yashao Chen (Author), Liquan Ou (Author), Zhenggen Liao (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2019-02-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Solid dispersion (SD) is a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble drugs. This work investigated the effects of carrier material lipophilicity and preparation method on the properties of andrographolide (AG)⁻SD. The SDs of AG and the carr...