Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment

• Main Authors: Maria Nikiforou (Author), Carolin Willburger (Author), Anja E de Jong (Author), Nico Kloosterboer (Author), Reint K Jellema (Author), Daan R M G Ophelders (Author), Harry W M Steinbusch (Author), Boris W Kramer (Author), Tim G A M Wolfs (Author)
• Format: Book
• Published: BMC, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Perinatal asphyxia, a condition of impaired gas exchange during birth, leads to fetal hypoxia-ischemia (HI) and is associated with postnatal adverse outcomes including intestinal dysmotility and necrotizing enterocolitis. Evidence from adult animal models of transient, locally induced intes...