Pharmacokinetics, Tissue Distribution, and Excretion Characteristics of a Radix Polygoni Multiflori Extract in Rats

• Main Authors: Wenhao Cheng (Author), Siyang Wu (Author), Zheng Yuan (Author), Weiyu Hu (Author), Xin Yu (Author), Nianxin Kang (Author), Qiutao Wang (Author), Mingying Zhu (Author), Kexin Xia (Author), Wei Yang (Author), Chen Kang (Author), Shuofeng Zhang (Author), Yingfei Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although progress has been achieved in the pharmacological activity and toxicity of Radix Polygoni Multiflori (RPM), the chemical basis of its toxicity is still unclear. Here, we performed a multicompound pharmacokinetic analysis and investigated the tissue distribution and excretion characteristics...