Ketamine as an antidepressant: overview of its mechanisms of action and potential predictive biomarkers

• Main Authors: Dmitriy Matveychuk (Author), Rejish K. Thomas (Author), Jennifer Swainson (Author), Atul Khullar (Author), Mary-Anne MacKay (Author), Glen B. Baker (Author), Serdar M. Dursun (Author)
• Format: Book
• Published: SAGE Publishing, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ketamine, a drug introduced in the 1960s as an anesthetic agent and still used for that purpose, has garnered marked interest over the past two decades as an emerging treatment for major depressive disorder. With increasing evidence of its efficacy in treatment-resistant depression and its potential...