Ivermectin and gemcitabine combination treatment induces apoptosis of pancreatic cancer cells via mitochondrial dysfunction

• Main Authors: Da Eun Lee (Author), Hyeon Woong Kang (Author), So Yi Kim (Author), Myeong Jin Kim (Author), Jae Woong Jeong (Author), Woosol Chris Hong (Author), Sungsoon Fang (Author), Hyung Sun Kim (Author), Yun Sun Lee (Author), Hyo Jung Kim (Author), Joon Seong Park (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic cancer is an aggressive cancer characterized by high mortality and poor prognosis, with a survival rate of less than 5 years in advanced stages. Ivermectin, an antiparasitic drug, exerts antitumor effects in various cancer types. This is the first study to evaluate the anticancer effects...