Oncolytic viral kinetics mechanistic modeling of Talimogene Laherparepvec (T‐VEC) a first‐in‐class oncolytic viral therapy in patients with advanced melanoma

Abstract Talimogene Laherparepvec (T‐VEC) is a first‐in‐class oncolytic virotherapy approved for the treatment of unresectable melanoma recurrent after initial surgery. Biodistribution data from a phase II study was used to develop a viral kinetic mechanistic model describing the interaction between...

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Bibliographic Details
Main Authors: Malidi Ahamadi (Author), Johannes Kast (Author), Po‐Wei Chen (Author), Xiaojun Huang (Author), Sandeep Dutta (Author), Vijay V. Upreti (Author)
Format: Book
Published: Wiley, 2023-02-01T00:00:00Z.
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