Shh Signaling from the Injured Lung Microenvironment Drives BMSCs Differentiation into Alveolar Type II Cells for Acute Lung Injury Treatment in Mice

• Главные авторы: Mengyu Wu (Автор), Jing Liu (Автор), Shu Zhang (Автор), Yi Jian (Автор), Ling Guo (Автор), Huacai Zhang (Автор), Junwei Mi (Автор), Guoxin Qu (Автор), Yaojun Liu (Автор), Chu Gao (Автор), Qingli Cai (Автор), Dalin Wen (Автор), Di Liu (Автор), Jianhui Sun (Автор), Jianxin Jiang (Автор), Hong Huang (Автор)
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• Опубликовано: Hindawi Limited, 2024-01-01T00:00:00Z.
• Предметы: article
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Alveolar type II (AT2) cells are key effector cells for repairing damaged lungs. Direct differentiation into AT2 cells from bone marrow mesenchymal stem cells (BMSCs) is a promising approach to treating acute lung injury (ALI). The mechanisms of BMSC differentiation into AT2 cells have not been dete...