Sex- and Disease-Specific Inflammasome Signatures in Circulating Blood Leukocytes of Patients with Abdominal Aortic Aneurysm

• Auteurs principaux: Xiaoyu Wu (Auteur), Sinan Cakmak (Auteur), Markus Wortmann (Auteur), Maani Hakimi (Auteur), Jian Zhang (Auteur), Dittmar Böckler (Auteur), Susanne Dihlmann (Auteur)
• Format: Livre
• Publié: BMC, 2016-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Male sex is a risk factor for abdominal aortic aneurysm (AAA). Within the AAA adventitia, infiltrating leukocytes express high levels of inflammasome components. To further elucidate the role of inflammatory cells in the pathogenesis of AAA, we here addressed expression and functionality of...