MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion

• Main Authors: Yebin Lu (Author), Xiaoli Zhang (Author), Xueyu Li (Author), Lingjie Deng (Author), Changqiang Wei (Author), Dongmei Yang (Author), Xuemei Tan (Author), Weicheng Pan (Author), Lihong Pang (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Spontaneous abortions (SA) is amongst the most common complications associated with pregnancy in humans, and the underlying causes cannot be identified in roughly half of SA cases. We found miR-135a-5p to be significantly upregulated in SA-associated villus tissues, yet the funct...