BasePhasing: a highly efficient approach for preimplantation genetic haplotyping in clinical application of balanced translocation carriers

• Hoofdauteurs: Shuo Zhang (Auteur), Dingding Zhao (Auteur), Jun Zhang (Auteur), Yan Mao (Auteur), Lingyin Kong (Auteur), Yueping Zhang (Auteur), Bo Liang (Auteur), Xiaoxi Sun (Auteur), Congjian Xu (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2019-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Preimplantation genetic testing (PGT) has already been applied in chromosomally balanced translocation carriers to improve the clinical outcome of assisted reproduction. However, traditional methods could not further distinguish embryos carrying a translocation from those with a...