Oral Antioxidant Vitamins and Magnesium Limit Noise-Induced Hearing Loss by Promoting Sensory Hair Cell Survival: Role of Antioxidant Enzymes and Apoptosis Genes

• Autors principals: Juan C. Alvarado (Autor), Verónica Fuentes-Santamaría (Autor), Pedro Melgar-Rojas (Autor), María C. Gabaldón-Ull (Autor), José J. Cabanes-Sanchis (Autor), José M. Juiz (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2020-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Noise induces oxidative stress in the cochlea followed by sensory cell death and hearing loss. The proof of principle that injections of antioxidant vitamins and Mg²⁺ prevent noise-induced hearing loss (NIHL) has been established. However, effectiveness of oral administration...