Nasal Delivery of Hesperidin/Chitosan Nanoparticles Suppresses Cytokine Storm Syndrome in a Mouse Model of Acute Lung Injury

• Main Authors: Hua Jin (Author), Zuguo Zhao (Author), Qian Lan (Author), Haotong Zhou (Author), Zesen Mai (Author), Yuan Wang (Author), Xiaowen Ding (Author), Wenting Zhang (Author), Jiang Pi (Author), Colin E. Evans (Author), Xinguang Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cytokine storm or cytokine storm syndrome (CSS) is associated with high mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), for example following sepsis or infectious diseases including COVID-19. However, there are no effective treatments for CSS-as...