Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence
Abstract Chronic lymphocytic leukemia (CLL) patients assigned to stereotyped subset 4 possess distinctive patterns of intraclonal diversification (ID) within their immunoglobulin (IG) genes. Although highly indicative of an ongoing response to antigen(s), the critical question concerning the precise...
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Main Authors: | Lesley-Ann Sutton (Author), Efterpi Kostareli (Author), Evangelia Stalika (Author), Athanasios Tsaftaris (Author), Achilles Anagnostopoulos (Author), Nikos Darzentas (Author), Richard Rosenquist (Author), Kostas Stamatopoulos (Author) |
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Format: | Book |
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BMC,
2013-08-01T00:00:00Z.
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