A systematic review of the clinical profile of patients with bubonic plague and the outcome measures used in research settings.

• Main Authors: Josephine Bourner (Author), Lovarivelo Andriamarohasina (Author), Alex Salam (Author), Nzelle Delphine Kayem (Author), Rindra Randremanana (Author), Piero Olliaro (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Plague is a zoonotic disease that, despite affecting humans for more than 5000 years, has historically been the subject of limited drug development activity. Drugs that are currently recommended in treatment guidelines have been approved based on animal studies alone-n...