De Novo Molecular Design of Caspase-6 Inhibitors by a GRU-Based Recurrent Neural Network Combined with a Transfer Learning Approach

• Asıl Yazarlar: Shuheng Huang (Yazar), Hu Mei (Yazar), Laichun Lu (Yazar), Minyao Qiu (Yazar), Xiaoqi Liang (Yazar), Lei Xu (Yazar), Zuyin Kuang (Yazar), Yu Heng (Yazar), Xianchao Pan (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Due to their potential in the treatment of neurodegenerative diseases, caspase-6 inhibitors have attracted widespread attention. However, the existing caspase-6 inhibitors showed more or less inevitable deficiencies that restrict their clinical development and applications. Therefore, there is an ur...