Interleukin-6 induced by YAP in hepatocellular carcinoma cells recruits tumor-associated macrophages

• Main Authors: Tian-yi Zhou (Author), Yu-lu Zhou (Author), Mei-jia Qian (Author), Yi-zheng Fang (Author), Song Ye (Author), Wen-xiu Xin (Author), Xiao-chun Yang (Author), Hong-hai Wu (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor-associated macrophages (TAMs) has been regarded as the most prominent component in tumor microenvironment. The correlation between TAM density and poor prognosis in Hepatocellular carcinoma (HCC) patients suggests a supportive role for TAMs in tumor progression. Here we employed a co-culture s...