Novel method of real-time PCR-based screening for common fetal trisomies

• Main Authors: So Yeon Kim (Author), Seung Mi Lee (Author), Sun Min Kim (Author), Byoung Jae Kim (Author), Ja Nam Koo (Author), Ig Hwan Oh (Author), Sohee Oh (Author), Chan-Wook Park (Author), Jong Kwan Jun (Author), Ji Hyae Lim (Author), Hyun Mee Ryu (Author), Joong Shin Park (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The non-invasive prenatal test (NIPT) is based on next generation sequencing (NGS) and is used for screening for fetal trisomy. However, it is time-consuming and technically difficult. Recently, peptide nucleic acid (PNA) probe-based real-time polymerase chain reaction (RT-PCR) w...