Plasma dopa decarboxylase activity in treatment-resistant recent-onset psychosis patients

• Main Authors: Marieke van der Pluijm (Author), Arjen L. Sutterland (Author), André B. P. van Kuilenburg (Author), Lida Zoetekouw (Author), Lieuwe de Haan (Author), Jan Booij (Author), Elsmarieke van de Giessen (Author)
• Format: Book
• Published: SAGE Publishing, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment resistance (TR) in psychosis is a major clinical problem. A biomarker predicting TR against conventional antipsychotic drugs would be relevant, potentially reducing unnecessary delay to adequate treatment with clozapine. Dopa decarboxylase (DDC) activity in the striatum, measured with posi...