Proteases Revisited: Roles and Therapeutic Implications in Fibrosis
Proteases target many substrates, triggering changes in distinct biological processes correlated with cell migration, EMT/EndMT and fibrosis. Extracellular protease activity, demonstrated by secreted and membrane-bound protease forms, leads to ECM degradation, activation of other proteases (i.e., pr...
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Hindawi Limited,
2017-01-01T00:00:00Z.
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