Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

• Main Authors: Liang Yue (Author), Nan Jiang (Author), Anguo Wu (Author), Wenqiao Qiu (Author), Xin Shen (Author), Dalian Qin (Author), Hong Li (Author), Jing Lin (Author), Sicheng Liang (Author), Jianming Wu (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stress injury and metabolic syndrome. Thus, XO activators may exhibit above potential toxicological properties. Plumbagin (PLB) is an important ac...