Dermatophagoides pteronyssinus-induced pro-inflammatory responses mediated via STAT3 and NF-kappaB signaling pathways in human bronchial epithelial cells - Inhibitory effects of Lafoensia pacari and ellagic acid

• Main Authors: Ana Letícia Júlio de Souza (Author), Aline Beatriz Mahler Pereira (Author), Jhony Robison de Oliveira (Author), Luciana Santos Ramalho (Author), Henrique Ismarsi de Souza (Author), Altina Lacerda Nascimento (Author), Mohib Uddin (Author), Paulo Sérgio Pereira (Author), David Nascimento Silva Teixeira (Author), Paulo Roberto da Silva (Author), Deijanira Alves de Albuquerque (Author), Lucia Helena Faccioli (Author), Alexandre de Paula Rogério (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The house dust mite allergen Dermatophagoides pteronyssinus (Der p) is a major driver of allergic asthma. Studies from our group demonstrated anti-eosinophilic effects of ethanolic extract of Lafoensia pacari stem bark (and ellagic acid, isolated from L. pacari extract), used as traditional medicine...