WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

• Main Authors: Mohammed A. F. Elewa (Author), Wagdy M. Eldehna (Author), Ahmed M. E. Hamdan (Author), Samraa H. Abd El-kawi (Author), Asmaa M. El-Kalaawy (Author), Taghreed A. Majrashi (Author), Reham F. Barghash (Author), Hatem A. Abdel-Aziz (Author), Khalid S. Hashem (Author), Mohammed M. H. Al-Gayyar (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma is considered one of the most lethal cancers, which is characterised by increasing prevalence associated with high level of invasion and metastasis. The novel synthetic pyrazolo[3,4-b]pyridine compound, WRH-2412, was reported to exhibit in vitro antitumor activity. This stud...