Population pharmacokinetics of intravenous colistin sulfate and dosage optimization in critically ill patients

• Main Authors: Yue-liang Xie (Author), Xin Jin (Author), Shan-shan Yan (Author), Cui-fang Wu (Author), Bi-xiao Xiang (Author), Hui Wang (Author), Wu Liang (Author), Bing-chang Yang (Author), Xue-fei Xiao (Author), Zhi-ling Li (Author), Qi Pei (Author), Xiao-cong Zuo (Author), Yue Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: To explore the population pharmacokinetics of colistin sulfate and to optimize the dosing strategy for critically ill patients.Methods: The study enrolled critically ill adult patients who received colistin sulfate intravenously for more than 72 h with at least one measurement of plasma concen...