CD40-mediated HIF-1α expression underlying microangiopathy in diabetic nerve pathology

• Main Authors: Hung-Wei Kan (Author), Jung-Hsien Hsieh (Author), Hsiung-Fei Chien (Author), Yea-Huey Lin (Author), Ti-Yen Yeh (Author), Chi-Chao Chao (Author), Sung-Tsang Hsieh (Author)
• Format: Book
• Published: The Company of Biologists, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To understand the pathology and molecular signatures of microangiopathy in diabetic neuropathy, we systemically and quantitatively examined the morphometry of microvascular and nerve pathologies of sural nerves. In the endoneurium of diabetic nerves, prominent microangiopathy was observed, as eviden...