An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes

Abstract Background Molecular mechanism of lung squamous cell carcinoma (LUSC) remains poorly understood, hampering effective targeted therapies or precision diagnosis about LUSC. We devised an integrative framework to investigate on the molecular patterns of LUSC by systematically mining the genomi...

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Main Authors: Zongang Liu (Author), Meiyan Deng (Author), Lin Wu (Author), Suning Zhang (Author)
Format: Book
Published: BMC, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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