Proteomic profiling of human plasma extracellular vesicles identifies PF4 and C1R as novel biomarker in sarcopenia

• Main Authors: Paula Aparicio (Author), David Navarrete‐Villanueva (Author), Alba Gómez‐Cabello (Author), Tresa López‐Royo (Author), Enrique Santamaría (Author), Joaquín Fernández‐Irigoyen (Author), Karina Ausín (Author), Manuel Arruebo (Author), Victor Sebastian (Author), Germán Vicente‐Rodríguez (Author), Rosario Osta (Author), Raquel Manzano (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sarcopenia, the gradual and generalized loss of muscle mass and function with ageing, is one of the major health problems in older adults, given its high prevalence and substantial socioeconomic implications. Despite the extensive efforts to reach consensus on definition and diag...