Population Pharmacokinetics and Initial Dose Optimization of Sirolimus Improving Drug Blood Level for Seizure Control in Pediatric Patients With Tuberous Sclerosis Complex

• मुख्य लेखकों: Xiao Chen (लेखक), Dongdong Wang (लेखक), Lin Zhu (लेखक), Jinmiao Lu (लेखक), Yidie Huang (लेखक), Guangfei Wang (लेखक), Yiqing Zhu (लेखक), Qiaofeng Ye (लेखक), Yi Wang (लेखक), Hong Xu (लेखक), Zhiping Li (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The purposes of this study were to explore the population pharmacokinetics and initial dose optimization of sirolimus improving drug blood level for seizure control in pediatric patients with tuberous sclerosis complex (TSC). Eighty pediatric patients diagnosed with TSC-related epilepsy were include...