MPET2: a multi-network poroelastic and transport theory for predicting absorption of monoclonal antibodies delivered by subcutaneous injection

• Main Authors: Hao Wang (Author), Tianyi Hu (Author), Yu Leng (Author), Mario de Lucio (Author), Hector Gomez (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

AbstractSubcutaneous injection of monoclonal antibodies (mAbs) has attracted much attention in the pharmaceutical industry. During the injection, the drug is delivered into the tissue producing strong fluid flow and tissue deformation. While data indicate that the drug is initially uptaken by the ly...