Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment

• প্রধান লেখক: Leelawadee Sriboonnark (লেখক), Harleen Arora (লেখক), Leyre Falto-Aizpurua (লেখক), Sonal Choudhary (লেখক), Elizabeth Alvarez Connelly (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Hindawi Limited, 2015-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We report the case of 17-year-old female diagnosed with Costello syndrome. Genetic testing provided a proof with G12S mutation in the HRAS gene since 3 years of age with a presentation of severe nodulocystic acne on her face. After 2 months of oral isotretinoin treatment, improvement in her acne was...