Anti-neuroinflammatory Activity of Kamebakaurin From Isodon japonicus via Inhibition of c-Jun NH2-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Pathway in Activated Microglial Cells

• Main Authors: Byung-Wook Kim (Author), Sushruta Koppula (Author), In Su Kim (Author), Hyung-Woo Lim (Author), Sun-Min Hong (Author), Sang-Don Han (Author), Bang-Yeon Hwang (Author), Dong-Kug Choi (Author)
• Format: Book
• Published: Elsevier, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Compelling evidence supports the notion that the majority of neurodegenerative diseases are associated with microglia-mediated neuroinflammation. Therefore, quelling of microglial activation may lead to neuronal cell survival. The present study investigated the effects of Kamebakaurin (KM...