Isosorbide and nifedipine for Chagas' megaesophagus: A systematic review and meta-analysis.

• Main Authors: Celina Borges Migliavaca (Author), Cinara Stein (Author), Verônica Colpani (Author), Sandro René Pinto de Sousa Miguel (Author), Luciane Nascimento Cruz (Author), Roberto Oliveira Dantas (Author), Maicon Falavigna (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Chagas disease is a neglected tropical disease. About 6 to 8 million people are chronically infected and 10% to 15% develop irreversible gastrointestinal disorders, including megaesophagus. Treatment focuses on improving symptoms, and isosorbide and nifedipine may be used for this purpose...