Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of goutengsan on methamphetamine dependence

• Main Authors: Han-Cheng Li (Author), Jie-Yu Li (Author), Xing-Chen Wang (Author), Ming Zeng (Author), Yang-Kai Wu (Author), Yi-Ling Chen (Author), Cai-Hua Kong (Author), Ke-Lin Chen (Author), Jie-Ru Wu (Author), Zhi-Xian Mo (Author), Jia-Xuan Zhang (Author), Chang-Shun Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundGoutengsan (GTS) is a traditional Chinese medicine formula that can improve multiple nervous system diseases, such as methamphetamine (MA) dependence. However, the mechanism how GTS treats MA dependence remains unclear. This study was aimed to investigate the action mechanism of GTS on MA...