Revolutionizing Drug Targeting Strategies: Integrating Artificial Intelligence and Structure-Based Methods in PROTAC Development

• Những tác giả chính: Danishuddin (Tác giả), Mohammad Sarwar Jamal (Tác giả), Kyoung-Seob Song (Tác giả), Keun-Woo Lee (Tác giả), Jong-Joo Kim (Tác giả), Yeong-Min Park (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2023-11-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

PROteolysis TArgeting Chimera (PROTAC) is an emerging technology in chemical biology and drug discovery. This technique facilitates the complete removal of the target proteins that are "undruggable" or challenging to target through chemical molecules via the Ubiquitin-Proteasome System (UP...