Automated radiosynthesis and in vivo evaluation of 18F-labeled analog of the photosensitizer ADPM06 for planning photodynamic therapy

• Main Authors: Kazunori Kawamura (Author), Tomoteru Yamasaki (Author), Masayuki Fujinaga (Author), Tomomi Kokufuta (Author), Yiding Zhang (Author), Wakana Mori (Author), Yusuke Kurihara (Author), Masanao Ogawa (Author), Kaito Tsukagoe (Author), Nobuki Nengaki (Author), Ming-Rong Zhang (Author)
• Format: Book
• Published: SpringerOpen, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A family of BF2-chelated tetraaryl-azadipyrromethenes was developed as non-porphyrin photosensitizers for photodynamic therapy. Among the developed photosensitizers, ADPM06 exhibited excellent photochemical and photophysical properties. Molecular imaging is a useful tool for phot...