Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network

• Main Authors: Annegret Holm (Author), Maroeska te Loo (Author), Leo Schultze Kool (Author), Päivi Salminen (Author), Veronica Celis (Author), Eulalia Baselga (Author), Sophie Duignan (Author), Veronika Dvorakova (Author), Alan D. Irvine (Author), Laurence M. Boon (Author), Miikka Vikkula (Author), Nader Ghaffarpour (Author), Charlotte M. Niemeyer (Author), Jochen Rössler (Author), Friedrich G. Kapp (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extensive lymphatic malformations (LMs) of the head and neck region may require tracheostomy to secure the airway. Treatment of these life-threatening LMs is usually multimodal and includes sclerotherapy and surgery, among others. Recently, systemic therapy with sirolimus has been introduced as an e...