Advanced Glycation End Product Accumulation in Subjects with Open-Angle Glaucoma with and without Exfoliation

• Main Authors: Tomoki Shirakami (Author), Mikihiro Yamanaka (Author), Jo Fujihara (Author), Yotaro Matsuoka (Author), Yuko Gohto (Author), Akira Obana (Author), Masaki Tanito (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advanced glycation end products (AGEs), which are the products of a non-enzymatic reaction between reducing sugars and other macromolecules, are critical in aging, as well as metabolic and degenerative diseases. To assess the involvement of AGEs in glaucoma, skin autofluorescence (sAF) level, which...