Tauroursodeoxycholic Acid Protects Retinal and Visual Function in a Mouse Model of Type 1 Diabetes

• Main Authors: Jieming Fu (Author), Moe H. Aung (Author), Megan C. Prunty (Author), Adam M. Hanif (Author), Lauren M. Hutson (Author), Jeffrey H. Boatright (Author), Machelle T. Pardue (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Previous studies demonstrated that systemic treatment with tauroursodeoxycholic acid (TUDCA) is protective in in vivo mouse models of retinal degeneration and in culture models of hyperglycemia. This study tested the hypothesis that TUDCA will preserve visual and retinal function in a mouse...