Immortalized stem cell-derived hepatocyte-like cells: An alternative model for studying dengue pathogenesis and therapy.

• Main Authors: Kessiri Kongmanas (Author), Nuntaya Punyadee (Author), Kasima Wasuworawong (Author), Adisak Songjaeng (Author), Tanapan Prommool (Author), Yongyut Pewkliang (Author), Siriphan Manocheewa (Author), Somchai Thiemmeca (Author), Khanit Sa-Ngiamsuntorn (Author), Chunya Puttikhunt (Author), Kym Francis Faull (Author), Suradej Hongeng (Author), Panisadee Avirutnan (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Suitable cell models are essential to advance our understanding of the pathogenesis of liver diseases and the development of therapeutic strategies. Primary human hepatocytes (PHHs), the most ideal hepatic model, are commercially available, but they are expensive and vary from lot-to-lot which confo...