Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect

• Main Authors: Miruna Negulescu (Author), Florian Deilhes (Author), Vincent Sibaud (Author), Emilie Tournier (Author), Laurence Lamant (Author), Serge Boulinguez (Author), Nicolas Meyer (Author)
• Format: Book
• Published: Karger Publishers, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The combination of MEK inhibitor (cobimetinib, trametinib) and BRAF inhibitor (vemurafenib, dabrafenib) is now the first-line treatment in patients with BRAF V600-mutated metastatic melanoma. This association reduces cutaneous adverse events induced by BRAF inhibitors alone, including photosensitivi...