In Vitro Metabolism and Transport Characteristics of Zastaprazan

• প্রধান লেখক: Min Seo Lee (লেখক), Jihoon Lee (লেখক), Minyoung Pang (লেখক), John Kim (লেখক), Hyunju Cha (লেখক), Banyoon Cheon (লেখক), Min-Koo Choi (লেখক), Im-Sook Song (লেখক), Hye Suk Lee (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Zastaprazan (JP-1366), a novel potassium-competitive acid blocker, is a new drug for the treatment of erosive esophagitis. JP-1366 is highly metabolized in human, mouse, and dog hepatocytes but moderately metabolized in rat and monkey hepatocytes when estimated from the metabolic stability of this c...