Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women.

• Main Authors: Pilar Requena (Author), Edmilson Rui (Author), Norma Padilla (Author), Flor E Martínez-Espinosa (Author), Maria Eugenia Castellanos (Author), Camila Bôtto-Menezes (Author), Adriana Malheiro (Author), Myriam Arévalo-Herrera (Author), Swati Kochar (Author), Sanjay K Kochar (Author), Dhanpat K Kochar (Author), Alexandra J Umbers (Author), Maria Ome-Kaius (Author), Regina Wangnapi (Author), Dhiraj Hans (Author), Michela Menegon (Author), Francesca Mateo (Author), Sergi Sanz (Author), Meghna Desai (Author), Alfredo Mayor (Author), Chetan C Chitnis (Author), Azucena Bardají (Author), Ivo Mueller (Author), Stephen Rogerson (Author), Carlo Severini (Author), Carmen Fernández-Becerra (Author), Clara Menéndez (Author), Hernando Del Portillo (Author), Carlota Dobaño (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P. vivax infection during pregnancy has been associated with poor outcomes such as anemia, low birth weight and congenital malaria, thus representing an important global health problem. However, no vaccine is currently available for its prevention. Vir genes were the first putative virulent factors...