Para-occupational exposure to pesticides, PON1 polymorphisms and hypothyroxinemia during the first half of pregnancy in women living in a Mexican floricultural area

• Main Authors: Luisa Torres-Sánchez (Author), Ricardo Gamboa (Author), Susana Bassol-Mayagoitia (Author), Claudia Huesca-Gómez (Author), Martha Patricia Nava (Author), Jennifer Illian Vázquez-Potisek (Author), Leticia Yáñez-Estrada (Author), Rebeca Mejía-Saucedo (Author), Julia Blanco-Muñoz (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Adequate maternal thyroxine (T4) concentrations during the first half of pregnancy are fundamental to the embryo's or fetus' neural development. Organophosphate pesticides (OP) can act as thyroid disruptors and genetic polymorphisms for paraoxonase 1 (PON1), an enzyme t...