Compound heterozygous WNT10A missense variations exacerbated the tooth agenesis caused by hypohidrotic ectodermal dysplasia

• Päätekijät: Yiting Liu (Tekijä), Jing Sun (Tekijä), Caiqi Zhang (Tekijä), Yi Wu (Tekijä), Siyuan Ma (Tekijä), Xuechun Li (Tekijä), Xiaoshan Wu (Tekijä), Qingping Gao (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2024-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background The aim of this study was to analyse the differences in the phenotypes of missing teeth between a pair of brothers with hypohidrotic ectodermal dysplasia (HED) and to investigate the underlying mechanism by comparing the mutated gene loci between the brothers with whole-exome seq...