Network pharmacology and experimental validation to explore the role and potential mechanism of Liuwei Dihuang Decoction in prostate cancer

• Main Authors: Xiangyang Zhan (Author), Haoze Li (Author), Jingyun Jin (Author), Xiran Ju (Author), Jiawei Gao (Author), Xinglin Chen (Author), Fuwen Yuan (Author), Jianyi Gu (Author), DongLiang Xu (Author), Guanqun Ju (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective To evaluate the anti-tumor effector of Liuwei Dihuang Decoction (LWDHD) in prostate cancer (PCa) and explore the potential mechanism using experimental validation, network pharmacology, bioinformatics analysis, and molecular docking. Methods CCK test, Clone formation assay and wou...