Counting synapses using FIB/SEM microscopy: a true revolution for ultrastructural volume reconstruction

• 主要な著者: Angel Merchan-Perez (著者), José-Rodrigo Rodriguez (著者), Lidia AlonsoNanclares (著者), Andreas Schertel (著者), Javier DeFelipe (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2009-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The advent of transmission electron microscopy (TEM) in the 1950’s represented a fundamental step in the study of neuronal circuits. The application of this technique soon led to the realization that the number of synapses changes during the course of normal life, as well as under certain pathologic...