Fetal development of subcutaneous white adipose tissue is dependent on Zfp423

• Main Authors: Mengle Shao (Author), Chelsea Hepler (Author), Lavanya Vishvanath (Author), Karen A. MacPherson (Author), Napoleon C. Busbuso (Author), Rana K. Gupta (Author)
• Format: Bog
• Udgivet: Elsevier, 2017-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Objective: Zfp423 is a multi zinc-finger transcription factor expressed in preadipocytes and mature adipocytes in vivo. Our recent work has revealed a critical role for Zfp423 in maintaining the fate of white adipocytes in adult mice through suppression of the beige cell thermogenic gene program; lo...