Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer

The targeting of gastrin-releasing peptide receptors (GRPR) was recently proposed for targeted therapy, e.g., radiotherapy. Multiple and frequent injections of peptide-based therapeutic agents would be required due to rapid blood clearance. By conjugation of the GRPR antagonist RM26 (D-Phe-Gln-Trp-A...

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Main Authors: Ayman Abouzayed (Author), Hanna Tano (Author), Ábel Nagy (Author), Sara S. Rinne (Author), Fadya Wadeea (Author), Sharmishtaa Kumar (Author), Kristina Westerlund (Author), Vladimir Tolmachev (Author), Amelie Eriksson Karlström (Author), Anna Orlova (Author)
Format: Book
Published: MDPI AG, 2020-10-01T00:00:00Z.
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3rd Floor Main Library

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