Comparison of neurons derived from mouse P19, rat PC12 and human SH-SY5Y cells in the assessment of chemical- and toxin-induced neurotoxicity

• Հիմնական հեղինակներ: Dina Popova (Հեղինակ), Jessica Karlsson (Հեղինակ), Stig O. P. Jacobsson (Հեղինակ)
• Ձևաչափ: Գիրք
• Հրապարակվել է: BMC, 2017-06-01T00:00:00Z.
• Խորագրեր: article
• Առցանց հասանելիություն: Connect to this object online.

Abstract Background Exposure to chemicals might be toxic to the developing brain. There is a need for simple and robust in vitro cellular models for evaluation of chemical-induced neurotoxicity as a complement to traditional studies on animals. In this study, neuronally differentiated mouse embryona...