Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis

• Main Authors: Jing Jin (Author), Ming Ji (Author), Rong Fu (Author), Mingjin Wang (Author), Nina Xue (Author), Qiong Xiao (Author), Jingpin Hu (Author), Xiaojian Wang (Author), Fangfang Lai (Author), Dali Yin (Author), Xiaoguang Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sphingosine-1-phosphate receptor subtype 1 (S1P1) is essential for lymphocyte egress from lymphoid organs into systemic circulation and provides a well-defined drug target for autoimmune disorders. IMMH001, also called SYL930, is a specific S1P1/S1P4/S1P5 modulator. Here, we investigated the potenti...