In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution.

• Main Authors: Gopinath Venugopal (Author), Jordan T Bird (Author), Charity L Washam (Author), Hayden Roys (Author), Anne Bowlin (Author), Stephanie D Byrum (Author), Tiffany Weinkopff (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania parasites cause cutaneous leishmaniasis (CL), a disease characterized by disfiguring, ulcerative skin lesions. Both parasite and host gene expression following infection with various Leishmania species has been investigated in vitro, but global transcriptional analysis following L. major...